Proceedings of Scientific Research Universidad Anáhuac. Multidisciplinary Journal of Healthcare https://revistas.anahuac.mx/psrua <p><strong><em>Proceedings of Scientific Research Universidad Anáhuac. </em><em>Multidisciplinary Journal of Healthcare</em> </strong>es el órgano oficial del Centro de Investigación en Ciencias de la Salud (CICSA) de la Facultad de Ciencias de la Salud de la Universidad Anáhuac México. Es una revista multidisciplinaria, con periodicidad semestral y de acceso libre. La revista acepta para su publicación artículos de investigación científica básica, clínica y epidemiológica. Se publican artículos enfocados en las siguientes áreas: medicina, nutrición, odontología, biotecnología, y terapia física y rehabilitación. La evaluación de los artículos incluye un proceso de revisión por pares (doble ciego) con la participación de investigadores reconocidos en sus áreas de especialidad, asegurando que se cumpla con una alta y rigurosa calidad científica.</p> Universidad Anáhuac México es-ES Proceedings of Scientific Research Universidad Anáhuac. Multidisciplinary Journal of Healthcare 2954-3541 <p>Todo el contenido intelectual que se encuentra en la presente publicación periódica se licencia al público consumidor bajo la figura de Creative Commons<sup>©</sup>, salvo que el autor de dicho contenido hubiere pactado en contrario o limitado dicha facultad a “<em>Proceedings of Scientific Research Universidad Anáhuac. Multidisciplinary Journal of Healthcare</em><sup>©</sup>” o “Universidad Anáhuac México<sup>©</sup>” por escrito y expresamente.</p> <p><em>Proceedings of Scientific Research Universidad Anáhuac. Multidisciplinary Journal of Healthcare</em> se distribuye bajo una <a href="https://creativecommons.org/licenses/by-nc-nd/4.0/">Licencia Creative Commons Reconocimiento-No comercial-Sin derivados 4.0 Internacional (CC BY-NC-ND 4.0).</a></p> <p>El autor conserva los derechos patrimoniales sin restricciones y garantiza a la revista el derecho de ser la primera publicación del trabajo. El autor es libre de publicar en cualquier otro medio su artículo, como un repositorio institucional.</p> Prediabetic patients evaluated with Quantose™ IR and their relationship with anthropometric measurements through bioelectrical impedance analysis https://revistas.anahuac.mx/psrua/article/view/1293 <p><strong>Introduction: </strong>New metabolomic biomarkers as Quantose™ IR and anthropometric measurements using bioelectrical impedance analysis (BIA) provide relevant information on patients with insulin resistance and prediabetes. Quantose<sup>TM</sup> IR is a novel metabolomic test to assess insulin resistance for screening and monitoring. Establishing a correlation between these variables is useful in clinical practice and, to our knowledge, there are no published studies that explore the relationship between Quantose™ IR and anthropometric measurements using BIA in patients with prediabetes. <strong>Objective</strong>: To evaluate the correlation between Quantose™ IR and BIA anthropometric variables (fat mass, FM; fat mass index, FMI; and body mass index, BMI) in Mexican patients with prediabetes, overweight, and obesity. <strong>Materials and Methods</strong>: This is an observational, transversal analytic study in 135 patients of both genders between 20 and 65 years of age, BMI 25.0–34.9, with diagnosis of prediabetes. The Quantose™ IR test was performed as well as anthropometric measurements (FM, FMI, and BMI) using BIA taken with Inbody 230<sup>TM</sup>. Pearson’s correlations and independent sample t-tests were estimated with a significance level of <em>p &lt; 0.05.</em> <strong>Results</strong>: 135 patients were studied; 77% were female, aged 46 years in average. The prevalence of insulin resistance by Quantose™ IR was 71.1%. A positive correlation was confirmed between Quantose™ IR and FM, FMI, and BMI (<em>p &lt; 0.05</em>). Patients with altered Quantose™ IR had higher FM, FMI, and BMI (<em>p &lt; 0.05</em>). <strong>Conclusion</strong>: The data here presented confirm the existence of a positive and statistically significant correlation between Quantose™ IR and anthropometric measurements using BIA. This information may be useful for diagnosis and treatment in prediabetic, overweight, and obese patients.</p> Vanessa Mota-Sanhuaa José Alberto Rojas Jiménez Diana Martínez Castañeda Alejandro Covarrubias-Cortés Georgina Flores García Sandra López Ríos Adriana Reyes Camacho José Antonio Jácome-Mondragón Blanca Velázquez Hernández Derechos de autor 2022 Vanessa Mota-Sanhuaa, José Alberto Rojas Jiménez, Diana Martínez Castañeda, Alejandro Covarrubias-Cortés, Georgina Flores García, Sandra López Ríos, Adriana Reyes Camacho, José Antonio Jácome-Mondragón, Blanca Velázquez Hernández http://creativecommons.org/licenses/by-nc-nd/4.0 2022-05-03 2022-05-03 2 3 5 10 10.36105/psrua.2022v2n3.01 Social networks and COVID-19 vaccination hesitancy in Mexican older adults https://revistas.anahuac.mx/psrua/article/view/1296 <p><strong>Introduction: </strong>The importance of social networks is growing, impacting everyday life. At this stage of global COVID-19 vaccination roll-out, hesitancy to get immunized is slowing this process; it is thought that this decision could be impacted by information shared on social networks. <strong>Objective: </strong>Determine whether the use of social networks is associated with the willingness to get the COVID-19 vaccine. <strong>Methods: </strong>This is a secondary analysis of the ENSANUT COVID-19 study, that measures the impact of the pandemic on the Mexican population. Only older adults, aged 65 years or older, were included in this work. Face to face interviews were performed to determine social network utilization, willingness to get vaccinated, and socio-demographic information on health and COVID-19. Bivariate analysis and logistic regression were performed. <strong>Results: </strong>From a total of 1,490 older adults, 59.3 % were women whose mean age was 73.5 (SD 6.8), and 53.3% (n = 795) were willing to get a COVID-19 vaccine when available. In an adjusted multivariate logistic regression model, WhatsApp was found to be a significant variable related to lower risk of vaccine hesitancy (OR 0.43, 95% CI, 0.2–0.85; p = 0.016). Other variables related to vaccine hesitancy were being a woman (OR 1.58, 95% CI, 2–1.23; p &lt; 0.001) and COVID-19 literacy (OR 1.32, 95% CI, 1.01–1.74; p = 0.047). <strong>Conclusion: </strong>The use of social networks such as WhatsApp is a factor that can influence older adult vaccination against COVID-19. Social networks, among other variables, should be taken into account when analyzing factors that lead to vaccination hesitancy in older adults.</p> Julio M. Fernandez-Villa Victoria Galnares-Carcoba Juan S. Solis-Mata Circe Flores-Ruiz Mario U. Perez-Zepeda Derechos de autor 2022 Julio M. Fernandez-Villa, Victoria Galnares-Carcoba, Juan S. Solis-Mata, Circe Flores-Ruiz, Mario U. Perez-Zepeda http://creativecommons.org/licenses/by-nc-nd/4.0 2022-05-03 2022-05-03 2 3 11 19 10.36105/psrua.2022v2n3.02 Effect of early or late nutritional intervention with psychological support on symptoms associated with Anorexia Nervosa: a comparative study https://revistas.anahuac.mx/psrua/article/view/1297 <p><strong>Introduction: </strong>Anorexia nervosa (AN) is a disease with increasing incidence and prevalence, favored by biological, psychological, familial, and social factors. Management must be interdisciplinary, involving the intervention of nutritionists and psychologists. Additionally, it is important to evaluate the effect of an early or a late onset of the intervention. <strong>Objective: </strong>To determine if early nutrition-based intervention along with psychological support leads to a decrease in the symptoms associated with Anorexia Nervosa, when compared with late intervention. <strong>Methods: </strong>To evaluate the above parameters, an exploratory study was proposed with a design of non-randomized clinical trial and a non-probability purposive sampling of n = 17 women with AN between 12 and 25 years of age (x̄ <em>= </em>16.8 ± 3.6). According to the moment of the nutritional intervention with psychological support, the 17 women were divided into two groups: Group 1 (n = 10) start the intervention in the first six months after the onset of the disease while Group 2 (n = 7) started 3 years after the disease. The nutritional and psychological carried out consisted of three phases: individualized nutritional assessment, design of the meal plan according to the metabolic needs of each patient and nutritional indications, and an individualized psychological intervention. Both interventions were carried out once a week for six months, for a total of 24 psychological and nutritional sessions. The physical variables of body mass index (BMI) and arm muscle area (AMA) were measured. To assess emotional changes, the body image dissatisfaction subscale of the Eating Disorder Inventory (EDI) was used. <strong>Results: </strong>Six months after follow-up, the results showed statistically significant changes in the BMI (p &lt;,0.01), AMA (p &lt;,0.01) and body image dissatisfaction (p &lt;,0.01) after the intervention. It was found that the early-intervention group presented lower values in BMI and AMA as compared to the late-intervention patients while both groups showed a marked reduction in body image dissatisfaction values. The late-intervention group presented the sharpest reduction. There was no significant difference in the variables BMI and AMA in the intragroup comparisons. <strong>Conclusion: </strong>The early-onset nutritional intervention with psychological support decreased the physical and emotional symptoms associated with AN.</p> Andrea Flores-Gamboa Rocío Ivonne de la Vega-Morales Lorena Tovar Barrientos J. Gerardo Serrano-Robles Nicole Matz-Zyman Antonio Ibarra Derechos de autor 2022 Andrea Flores-Gamboa, Rocío Ivonne de la Vega-Morales, Lorena Tovar Barrientos, J. Gerardo Serrano-Robles, Nicole Matz-Zyman, Antonio Ibarra http://creativecommons.org/licenses/by-nc-nd/4.0 2022-05-03 2022-05-03 2 3 20 26 10.36105/psrua.2022v2n3.03 Bioinformatics approaches for Biomedical Research https://revistas.anahuac.mx/psrua/article/view/1299 <p>An enormous amount of data is generated and compiled in several databases every year. Along with this, comes a demand for the analysis and interpretation of the entirety of this biological information. Taking care of this task, bioinformatics promises breakthroughs in research and development in complex biomedical areas. In just a few years since its beginning, bioinformatics has led to great progress and demonstrated its potential. It has created an opportunity to solve arising medical and molecular issues faster and more efficiently, as compared to the traditional approach. The present review aims to present some of the main applications of bioinformatics in the field of biomedicine, such as comparative genomics, biomarker identification, computer-aided drug design, vaccine design, and personalized medicine. In addition, we also cover some of its steadily reduced limitations.</p> Kasandra Aguilar Cázarez Ernesto Andrade Collantes Marisol Verdugo Meza Claudia María de-la-Rocha-Morales Cruz Fernando López-Carrera Paúl Alexis López-Durán Derechos de autor 2022 Kasandra Aguilar Cázarez, Ernesto Andrade Collantes, Marisol Verdugo Meza, Claudia María de-la-Rocha-Morales, Cruz Fernando López-Carrera, Paúl Alexis López-Durán http://creativecommons.org/licenses/by-nc-nd/4.0 2022-05-03 2022-05-03 2 3 27 35 10.36105/psrua.2022v2n3.04 Philadelphia-positive atypical chronic myeloid leukemia, BCR/ABL negative: a case report https://revistas.anahuac.mx/psrua/article/view/1300 <p>Atypical myeloid leukemia is a myeloproliferative neoplasm in which patients have a dysplastic increase in blood cells of the myeloid lineage as a result of hypercellular bone marrow. Our patient presented a positive Ph karyotype and a negative ABL/BCR transcript. Moreover, her age does not correspond to the mean of diagnosis. Her first treatment was hydroxyurea 1 g/kg for 60 days, which was not positive for the evolution of the disease and thus the elective treatment was changed to imatinib 400 mg/ day. After two months, the treatment has produced a favorable response, which leads to think that the therapy with imatinib offers better clinical results than other conventional ones. This text presents the study carried out at the Manuel Ávila Camacho National Medical Center and compares it with the existing literature regarding diagnosis and treatment to assess similarities and highlight specific points that may help in future case management.</p> <p> </p> Germán Rivera Monroy Federica Riccio Cuomo Dunia Michelle Bustos Campa Jorge Luis López Marthen Derechos de autor 2022 Germán Rivera Monroy, Federica Riccio Cuomo, Dunia Michelle Bustos Campa, Jorge Luis López Marthen http://creativecommons.org/licenses/by-nc-nd/4.0 2022-05-03 2022-05-03 2 3 36 40 10.36105/psrua.2022v2n3.05