The Triangle of Decadence in ethics dumping and unethical research with Indigenous peoples

Main Article Content

Carlos Alberto Rosas Jiménez
https://orcid.org/0000-0003-1529-3785

Abstract




This study documents some elements of unethical research involving Indigenous populations, including lack of informed consent of participants, lack of community involvement for consultation or permission for use of data or biological samples collected, and concerns about cultur- al sensitivity. The Triangle of Decadence has been proposed as a pos- sible way to promote a change of mentality among researchers that helps to identify the core problems of unethical research. It gives a possible explanation of what triggers ethical dumping, describing the three points as 1) abuse of power, 2) ignorance of ethical research regulations, and 3) economic interests, and in the middle of the triangle is 4) the silence and complicity of third parties that aggravate the situation. Possible solutions to these problems are presented. Finally, we explain that there is also a risk of selective representation and tokenization of Indigenous communities.




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Rosas Jiménez, C. A. . (2025). The Triangle of Decadence in ethics dumping and unethical research with Indigenous peoples. Medicina Y Ética, 36(2), 456–502. https://doi.org/10.36105/mye.2025v36n2.01
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References

Shamoo A, Resnik D. The Protection of Human Subjects in Research. In: Resnik DB, editor. The Ethics of Research of Research with Human Subjects. New York, NY: Oxford University Press, 2009. DOI: https://doi.org/10.1093/acprof:oso/9780195368246.003.0012

Bianchi L, Babyak J, Maholic R. Research with Human Subjects. Research during Medical Residency. 2022; 107-38. https://doi.org/10.1201/9781003126478-8 DOI: https://doi.org/10.1201/9781003126478-8

Spellecy R, Busse K. The History of Human Subjects Research and Rationale for Institutional Review Board Oversight. Nutrition in clinical practice. 2021; 36(3):560-7. https://doi.org/10.1002/ncp.10623 DOI: https://doi.org/10.1002/ncp.10623

Eba J, Nakamura K. Overview of the ethical guidelines for medical and biologicalresearch involving human subjects in Japan. Japanese Journal of Clinical Oncology. 2022; 52(6):539-44. https://doi.org/10.1093/jjco/hyac034 DOI: https://doi.org/10.1093/jjco/hyac034

White M. Why Human Subjects Research Protection Is Important. Ochsner Journal. 2020; 20(1):16-33. https://doi.org/10.31486/toj.20.5012 DOI: https://doi.org/10.31486/toj.20.5012

Bercovitch L, Perlis CS, Stoff BK, Grant-Kels JM, Kosche C, Rolader R. Respect

for Human Subjects: Ethics in Research Design. Dermatoethics. 2021; 433-43. DOI: https://doi.org/10.1007/978-3-030-56861-0_41

Knight J. The need for improved ethics guidelines in a changing research landscape. South African Journal of Science. 2019; 115(11/12). https://doi.org/10.17159/sajs.2019/6349 DOI: https://doi.org/10.17159/sajs.2019/6349

López-Pacheco M, Pimentel-Hernández C, Rivas-Mirelles E, Arredondo-García J. Normatividad que rige la investigación clínica en seres humanos y requisitos que debe cumplir un centro de investigación para participar en un estudio clínico en México. Acta pediátrica de México: APM. 2016; 37(3):175. https://doi.org/10.18233/ APM37No3pp175182 DOI: https://doi.org/10.18233/APM37No3pp175-182

Behera S, Das S, Xavier A, Selvarajan S, Anandabaskar N. Indian Council of Medical Research’s National Ethical Guidelines for biomedical and health research involving human participants: The way forward from 2006 to 2017. Perspectives in clinical research. 2019; 10(3):108. https://doi.org/10.4103/picr.PICR_10_18 DOI: https://doi.org/10.4103/picr.PICR_10_18

Guillemin M, Gillam L, Barnard E, Stewart P, Walker H, Rosenthal D. “We’rechecking them out”: Indigenous and non-Indigenous research participants’ accounts of deciding to be involved in research. International Journal for Equity in Health. 2016; 15(1). https://doi.org/10.1186/s12939-016-0301-4 DOI: https://doi.org/10.1186/s12939-016-0301-4

Hajik MT. Ethics and Responsibility of Post-Colonial Allyness. Waterloo: The University of Western Ontario; 2016.

Wolfe P. Settler colonialism and the elimination of the native Journal of Genocide Research. 2006; 8(4):387-409. https://doi.org/10.1080/14623520601056240 DOI: https://doi.org/10.1080/14623520601056240

Willows N. Ethical principles of health research involving Indigenous peoples. Applied physiology, nutrition and metabolism Physiologie appliquée, nutrition et métabolisme. 2013; 38(11):iii-v. https://doi.org/10.1139/apnm-2013-0381 DOI: https://doi.org/10.1139/apnm-2013-0381

Macdonald N, Stanwick R, Lynk A. Canada’s shameful history of nutrition research on residential school children: The need for strong medical ethics in Aboiginal health research. Paediatrics & Child Health. 2014; 19(2):64-. https://doi.org/10.1093/pch/19.2.64 DOI: https://doi.org/10.1093/pch/19.2.64

Ortiz-Prado E, Simbaña-Rivera K, Gómez-Barreno L, Tamariz L, Lister A, Baca JC. Potential research ethics violations against an indigenous tribe in Ecuador: a mixed methods approach. BMC medical ethics. 2020; 21(1):1. https://doi. org/10.1186/s12910-020-00542-x DOI: https://doi.org/10.1186/s12910-020-00542-x

Hodge F. No Meaningful Apology for American Indian Unethical Research Abuses. Ethics & Behavior. 2012; 22(6):431-44. https://doi.org/10.1080/10508422.20 12.730788 DOI: https://doi.org/10.1080/10508422.2012.730788

Ermine W, Sinclair R, Jeffery B. The Ethics of Research involving Indigenous Peoples. Saskatoon, Canada: Indigenous Peoples’ Health Research Centre to the Interagency Advisory Panel on Research Ethics; 2004.

The World Bank. Indigenous Peoples 2023. Disponible en: https://www.worldbank.org/en/topic/indigenouspeoples#:~:text=There%20are%20an%20estimated%20476,of%20non%2DIndigenous%20Peoples%20worldwide

United Nations. Declaration on the Rights of Indigenous Peoples; 2007.

CEPAL. Los pueblos indígenas en América Latina. Avances en el último decenio y retos pendientes para la garantía de sus derechos. Santiago de Chile; 2014.

Montoya L. Autobiografía. Tomo I. Medellín, Colombia: Imprenta Departamental de Antioquia; 2005.

UNESCO. Local Knowledge,Global Goals. Paris: UNESCO; 2017.

Matsui K. Problems of Defining and Validating Traditional Knowledge: A Historical Approach. International Indigenous Policy Journal. 2015; 6(2). https://doi.org/10.18584/iipj.2015.6.2.2 DOI: https://doi.org/10.18584/iipj.2015.6.2.2

Mistry J. Indigenous knowledges. In: Kitchin R, Thrift N, editors. International En- cyclopedia of Human Geography. 5: Elsevier; 2009. DOI: https://doi.org/10.1016/B978-008044910-4.00101-2

Zidny R, Sjöström J, Eilks I. A Multi-Perspective Reflection on How Indigenous Knowledge and Related Ideas Can Improve Science Education for Sustainability. Science & Education. 2020; 29(1):145-85. https://doi.org/10.1007/s11191-019-00100-x DOI: https://doi.org/10.1007/s11191-019-00100-x

Mapedza E, Rashirayi T, Xueliang C, Haile AT, van Koppen B, Ndiyoi M. Indige- nous Knowledge Systems for the management of the Barotse Flood Plain in Zambia and their implications for policy and practice in the developing world. Indigenous Water and Drought Management in a Changing World. 2022; 4:209-25. https://doi.org/10.1016/B978-0-12-824538-5.00011-X DOI: https://doi.org/10.1016/B978-0-12-824538-5.00011-X

Grenier L. Working with Indigenous Knowledge: A Guide for Researchers.Ottawa: International Development Research Center; 1998.

Karmakar R, Rakshit A. Indigenous Knowledge Systems Perception, Documentation and Threat. In: Roy AK, editor. Information and Knowledge Management

Smith-Morris C. Indigenous communalism. Belonging, healthy communities, and decolonizing the collective. New Brunswick, NJ.: Rutgers University Press; 2020. DOI: https://doi.org/10.36019/9781978805446

Held M. Decolonizing Research Paradigms in the Context of Settler Colonialism: An Unsettling, Mutual, and Collaborative Effort. International Journal of Qualitative Methods.2019;18:160940691882157. https://doi.org/10.1177/1609406918821574 DOI: https://doi.org/10.1177/1609406918821574

Thompson J. Joyfully Living an Integral Ecology: Indigenous Narratives and Their Contribution to the Dialogue on Well-Being. The Heythrop Journal. 2018;59(6):969-82. https://doi.org/10.1111/heyj.13019 DOI: https://doi.org/10.1111/heyj.13019

Absolon K, Absolon J-A, Brasher L. Indigenous/Anishinaabek Wholistic Healing.

In: Dunn PA, editor. Holistic Healing Theories, Practices, and Social Change. Toronto: Canadian Scholars, an imprint of CSP Books, Inc.; 2019.

Barnhardt R, Kawagley A. Indigenous Knowledge Systems and Alaska Native Ways of Knowing. Anthropology & Education Quarterly. 2005; 36(1):8-23. https://doi.org/10.1525/aeq.2005.36.1.008 DOI: https://doi.org/10.1525/aeq.2005.36.1.008

Febria C, Donaldson C, Ives J, Keeshig K. Pluralistic approaches in research aim to advance farming and freshwater restoration in the Great Lakes basin. Pluralism in ecosystem governance /. 2022; 66:201-41. https://doi.org/10.1016/bs.aecr.2022.04.007 DOI: https://doi.org/10.1016/bs.aecr.2022.04.007

Fernández-Llamazares Á, Cabeza M. Rediscovering the Potential of Indigenous Storytelling for Conservation Practice. Conservation Letters. 2018; 11(3):e12398. https://doi.org/10.1111/conl.12398 DOI: https://doi.org/10.1111/conl.12398

Mcgregor D. Coming Full Circle: Indigenous Knowledge, Environment, and Our Future. The American Indian Quarterly. 2004; 28(3):385-410. https://doi.org/10.1353/aiq.2004.0101 DOI: https://doi.org/10.1353/aiq.2004.0101

Adejumo A. Socio-Cultural Factors Influencing Consent for Research in Nigeria: Lessons from Pfizer’s Trovan Clinicial Trial. African Journal for the Psychological Study of Social Issues. 2008; 11(2):229-38.

Ahmad K. Drug company sued over research trial in Nigeria. The Lancet. 2001; 358(9284):815. https://doi.org/10.1016/S0140-6736(01)06011-1 DOI: https://doi.org/10.1016/S0140-6736(01)06011-1

Fitzpatrick E, Martiniuk A, D’Antoine H, Oscar J, Carter M, Elliott E. Seeking con- sent for research with indigenous communities: a systematic review. BMC Medical Ethics. 2016; 17(1). https://doi.org/10.1186/s12910-016-0139-8 DOI: https://doi.org/10.1186/s12910-016-0139-8

TauriJ. Research ethics, informed consent and the disempowerment of First Nation peoples. Research Ethics. 2018; 14(3):1-14. https://doi.org/10.1177/1747016117739935 DOI: https://doi.org/10.1177/1747016117739935

Moodie S. Power, rights, respect and data ownership in academic research with indigenous peoples. Environmental research. 2010; 110(8):818-20. https://doi.org/10.1016/j.envres.2010.08.005 DOI: https://doi.org/10.1016/j.envres.2010.08.005

Nowrouzi B, McGregor L, McDougall A, Debassige D, Casole J. Ethics of Biological Sampling Research with Aboriginal Communities in Canada. Global Journal of Health Science. 2016; 9(4):20-30. https://doi.org/10.5539/gjhs.v9n4p20 DOI: https://doi.org/10.5539/gjhs.v9n4p20

Schroeder D, Chatfield K, Muthuswamy V, Kumar NK. Ethics Dumping –How not to do research in resource-poor settings. Academics Stand Against Poverty. 2021; 1(1):32-55. https://doi.org/10.5281/zenodo.8089799

Teixeira J. Handling Ethics Dumping and Neo-Colonial Research: From the Laboratory to the Academic Literature. Journal of Bioethical Inquiry. 2022; 19(3):433- 43. https://doi.org/10.1007/s11673-022-10191-x DOI: https://doi.org/10.1007/s11673-022-10191-x

Bassey-Orovwuje M, Thomas J, Wakeford T. Exterminator Genes: The Right to Say No to Ethics Dumping. Development. 2019; 62(1-4):121-7. https://doi.org/10.1057/s41301-019-00214-3 DOI: https://doi.org/10.1057/s41301-019-00214-3

Novoa-Heckel G, Bernabe R, Linares J. Exportation of unethical practices to low and middle income countries in biomedical research. Revista de Bioética y Bioderecho. 2017; 40:167-77. Available at: https://www.redalyc.org/articulo.oa?id=78351101013

Schroeder D, Chatfield K, Singh M, Chennells R, Herissone-Kelly P. Ethics Dumping and the Need for a Global Code of Conduct. Equitable Research Partnerships: Springer International Publishing; 2019. DOI: https://doi.org/10.1007/978-3-030-15745-6

Cook J. Avoiding Gender Exploitation and Ethics Dumping in Research with Women. Cambridge Quarterly of Healthcare Ethics. 2020; 29(3):470-9. https://doi.org/10.1017/S0963180120000213 DOI: https://doi.org/10.1017/S0963180120000213

Chatfield K, Schroeder D, Guantai A, Bhatt K, Bukusi E, Adhiambo Odhiambo J. Preventing ethics dumping: the challenges for Kenyan research ethics committees. Research Ethics. 2021; 17(1):23-44. https://doi.org/10.1177/1747016120925064 DOI: https://doi.org/10.1177/1747016120925064

Cyranoski D. The CRISPR-baby scandal: what’s next for human gene-editing. Nature. 2019; 566(7745):440-2. https://doi.org/10.1038/d41586-019-00673-1 DOI: https://doi.org/10.1038/d41586-019-00673-1

Greely H. CRISPR’d babies: human germline genome editing in the ‘He Jiankui affair’*. Journal of Law and the Biosciences. 2019; 6(1):111-83. https://doi.org/10.1093/jlb/lsz010 DOI: https://doi.org/10.1093/jlb/lsz010

Liao B, Ma Y, Lei R. Analysis of ethics dumping and proposed solutions in the field of biomedical research in China. Frontiers in Pharmacology. 2023;14. https://doi.org/10.3389/fphar.2023.1214590 DOI: https://doi.org/10.3389/fphar.2023.1214590

Chen Q, Ma Y, Labude M, Schaefer G, Xafis V, Mills P. Making sense of it all: Ethical reflections on the conditions surrounding the first genome-edited babies. Wellcome Open Research. 2021; 5:216. https://doi.org/10.12688/wellcomeopenres.16295.2 DOI: https://doi.org/10.12688/wellcomeopenres.16295.2

Merriam-Webster’s Collegiate Dictionary.

Fakruddin M, Mannan K, Chowdhury A, Mazumdar R, Hossain M, Afroz H. Research involving Human Subjects - Ethical Perspective. Bangladesh Journal of Bioethics. 2013; 4(2):41-8. https://doi.org/10.3329/bioethics.v4i2.16375 DOI: https://doi.org/10.3329/bioethics.v4i2.16375

MacLean L, Posner E, Thomson S, Wood EJ. Research Ethics and Human Subjects: A Reflexive Openness Approach. 2019. Report No.: 1556-5068.

Costeniuc M. Autonomy and Responsibility of the Researcher in Research on Human Subjects. Eastern-European Journal of Medical Humanities and Bioethics. 2019; 3(1):1-10. https://doi.org/10.18662/eejmhb.16 DOI: https://doi.org/10.18662/eejmhb.16

Mukherjee A. Revisiting the Ethical Aspects in Research Publications. International Research Journal of Multidisciplinary Scope. 2020; 1(1):27-9. https://doi.org/10.47857/irjms.2020.v01i01.005 DOI: https://doi.org/10.47857/irjms.2020.v01i01.005

Gallent C. Editorial misconduct: the case of online predatory journals. Heliyon. 2022; 8(3):e08999. https://doi.org/10.1016/j.heliyon.2022.e08999 DOI: https://doi.org/10.1016/j.heliyon.2022.e08999

Finlay S, Doyle M, Kennedy M. Aboriginal and Torres Strait Islander Human Re- search Ethics Committees (HRECs) are essential in promoting our health and wellbeing. Public Health Research & Practice. 2023; 33(2). https://doi.org/10.17061/phrp3322312 DOI: https://doi.org/10.17061/phrp3322312

Bain L. Revisiting the need for virtue in medical practice: A reflection upon the teaching of Edmund Pellegrino. Philosophy, Ethics, and Humanities in Medicine. 2018; 13(1):1-5. https://doi.org/10.1186/s13010-018-0057-0 DOI: https://doi.org/10.1186/s13010-018-0057-0

Fournier C, Stewart S, Adams J, Shirt C, Mahabir E. Systemic disruptions: deco- lonizing indigenous research ethics using indigenous knowledges. Research Ethics. 2023; 19(3):325-40. https://doi.org/10.1177/17470161231169205 DOI: https://doi.org/10.1177/17470161231169205

Salzano FM, Hurtado M. Lost Paradises and the Ethics of Research and Publication. Oxford: Oxford; 2004.

Brockie T, Hill K, Davidson P, Decker E, Krienke LK, Nelson K. Strategies for culturally safe research with Native American communities: an integrative review. Contemporary Nurse. 2022; 58(1):8-32. https://doi.org/10.1080/10376178.2021.2015414 DOI: https://doi.org/10.1080/10376178.2021.2015414

Rothstein M. Ethical Research and Minorities. American Journal of Public Health. 2013; 103(12):2118. https://doi.org/10.2105/AJPH.2013.301390 DOI: https://doi.org/10.2105/AJPH.2013.301390

George L, Tauri J, Tu MacDonald T. Indigenous Research Ethics: Claiming Re- search Sovereignty Beyond Deficit and the Colonial Legacy. Iphofen R, editor. Bingley, United Kingdom: Emerald Publishing Limited; 2020. DOI: https://doi.org/10.1108/S2398-6018202006

Morton M, Pollock N. Reconciling community-based Indigenous research and academic practices: Knowing principles is not always enough. Social science & medicine. 2017; 172:28-36. https://doi.org/10.1016/j.socscimed.2016.11.007 DOI: https://doi.org/10.1016/j.socscimed.2016.11.007

Ilyas H. Digging up a Buried Past: Reconciliand the Historical Injustices of Unethical Medical and Anthropological Research with Current Indigenous Studies of the Ainu Peoples. Tucson, Arizona: University of Arizona; 2020.

Johnstone M-J. Research ethics, reconciliation, and strengthening the research relationship in Indigenous health domains: An Australian perspective. International journal of intercultural relations. 2007; 31(3):391-406. https://doi.org/10.1016/j.ijintrel.2006.09.003 DOI: https://doi.org/10.1016/j.ijintrel.2006.09.003

Hayward A, Sjoblom E, Sinclair S, Cidro J. A New Era of Indigenous Research: Community-based Indigenous Research Ethics Protocols in Canada. Journal of Empirical Research on Human Research Ethics. 2021; 16(4):403-17. https://doi.org/10.1177/15562646211023705 DOI: https://doi.org/10.1177/15562646211023705

First Nations Information Governance Center. Ownership, Control, Access and Possession (OCAPTM): The Path to First Nations Information Governance. Ottawa; 2014.

Carroll SR, Garba I, Plevel R, Small-Rodriguez D, Hiratsuka VY, Hudson M.Using Indigenous Standards to Implement the CARE Principles: Setting Expectations through Tribal Research Codes. Frontiers in Genetics. 2022; 13. https://doi.org/10.3389/fgene.2022.823309 DOI: https://doi.org/10.3389/fgene.2022.823309

Kral M. Community Participation as an Ethical Principle for Research. International review of qualitative research. 2018; 11(2):148-57. Available at: https://www.academia.edu/102386932/Community_Participation_as_an_Ethical_Principle_ for_Research DOI: https://doi.org/10.1525/irqr.2018.11.2.148

Burnette C, Sanders S, Butcher H, Rand J. A Toolkit for Ethical and Culturally Sensitive Research: An Application with Indigenous Communities. Ethics and Social Welfare. 2014; 8(4):364-82. https://doi.org/10.1080/17496535.2014.885987 DOI: https://doi.org/10.1080/17496535.2014.885987

Khedr R, Etmanski A. Nothing About Us Without Us2021. Disponible en: https://www.disabilitywithoutpoverty.ca/nothing-about-us-without-us/

Marsden N, Star L, Smylie J. Nothing about us without us in writing: aligning the editorial policies of the Canadian Journal of Public Health with the inherent rights of Indigenous Peoples. Canadian Journal of Public Health. 2020; 111(6):822-5. https://doi.org/10.17269/s41997-020-00452-w DOI: https://doi.org/10.17269/s41997-020-00452-w

Funnell S, Tanuseputro P, Letendre A, Bearskin LB, Walker J.“Nothing About Us, without Us.” How Community-Based Participatory Research Methods Were Adapted in an Indigenous End-of-Life Study Using Previously Collected Data. Cana-dian Journal on Aging / La Revue canadienne du vieillissement. 2020; 39(2):145- 55. https://doi.org/10.1017/S0714980819000291 DOI: https://doi.org/10.1017/S0714980819000291

Harbord C, Hung P, Falconer R, editors. “Nothing about us, without us”. The 39th ACM International Conference on Design of Communication; 2021 2021- 10-12: ACM. DOI: https://doi.org/10.1145/3472714.3473657

Narr H. Nothing About Us Without Us. Access for Indigenous Peoples to the Uni- ted Nations and Perceptions of Legitimacy. Tübingen: Universität Tübingen; 2019.

Bourgeois-Doyle D. Two-Eyed AI. A reflection on Artificial Intelligence. Ottawa: Canadian Commission for UNESCO’s IdeaLab; 2019.

Kianpour C. The political speech rights of the tokenized. Critical Review of International Social and Political Philosophy. 2023:1-21. https://doi.org/10.1080/13698230.2023.2234801 DOI: https://doi.org/10.1080/13698230.2023.2234801

SchraubD.TheDistinctivePoliticalStatusofDissidentMinorities.AmericanPolitical Science Review. 2020; 114(4):963-75. https://doi.org/10.1017/S0003055420000659 DOI: https://doi.org/10.1017/S0003055420000659

Enari D, Keung S. Indigenizing Sport: Beyond Tokenism. In: Ravulo J, Olcoń K, Dune T, Workman A, Liamputtong P, editors. Handbook of critical whiteness: De- constructing dominant discourses across disciplines. Singapore: Springer Nature

Singapore; 2024.