This final edition of the year brings together a set of contributions that, from diverse angles, underscore the pressing need to reclaim the humanistic dimension of medical practice in the face of today’s bioethical challenges. The articles explore issues such as the legal and ethical debate over the “right to die” in France, the discriminatory risks posed by algorithmic bias in artificial intelligence, and the dangers of dehumanization linked to rapid technological advances in healthcare. They also reflect on the primacy of human dignity in caring for vulnerable patients, the value of incorporating the humanities into medical education, and the ethical tensions created by behavioral tools such as nudges, which challenge the balance between autonomy and beneficence.

In addition, the issue offers an examination of oral cancer, highlighting both its biomedical and social implications, with a strong emphasis on early detection and compassionate support. A review of the volume La vida humana naciente, edited by Justo Aznar, provides an interdisciplinary perspective that affirms the dignity of life from conception, addressing threats posed by emergency contraception, assisted reproduction, and embryo experimentation. Collectively, these contributions call for a balance between scientific progress and a bioethics rooted in dignity, justice, solidarity, and the holistic care of the human person.